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Fast and sensitive bioanalysis using micromachined electrospray interfaces with μ-scale separations

Department 58 – International Relations
Department 58 – International Relations

Published

Project
Region South Moravian Region
Title of the ProgrammeResearch
Title of the ProjectFast and sensitive bioanalysis using micromachined electrospray interfaces with μ-scale separations
Project Website

ubiosep.com
ubiosep.eu
facebook.com/ubiosep
instagram.com/ubiosep/
linkedin.com/company/ubiosep/

Number of the ProjectTO01000232
Project Promoter

Ústav analytické chemie AV ČR,v. v. i.

Project Partner from Donor State

SINTEF AS

Czech Partner

WATREX Praha, s.r.o.

Status

Estimated project duration: 10 / 2020 - 4 / 2024

Total Eligible Costs

1 294 955 EUR

Grant

1 183 069 EUR

Project description:

Main goals are:

  1. Development of micromachined ionization interfaces allowing highly sensitive mass spectrometry analysis of pre-separated biochemical compounds.
  2. Development of micromachined separation system utilizing the own patented principle of recycling chromatography in which the sample passes repeatedly though the (micro)separation column leading to a significant increase of resolution of its components.
  3. Development of methodology for coupling of conventional microcolumn-based separation and on-a-chip separation techniques to mass spectrometer through the micromachined interfaces.
  4. Demonstration of innovation potential of the developed technologies by showcasing two demonstrators targeting high impact applications relevant for life sciences and pharma industries.